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  • Perforation (Performed by Dr. Enry Garcia, DipACVO)
  • Descemetocele(Performed by Dr. Enry Garcia, DipACVO)
  • Descemetocele(Performed by Dr. Enry Garcia, DipACVO)
  • Healing Pattern(Performed by Dr. Enry Garcia, DipACVO)
  • Corneal Sequestrum (Performed by Dr. Enry Garcia, DipACVO)
Perforation (Performed by Dr. Enry Garcia, DipACVO)
Descemetocele(Performed by Dr. Enry Garcia, DipACVO)
Descemetocele(Performed by Dr. Enry Garcia, DipACVO)
Healing Pattern(Performed by Dr. Enry Garcia, DipACVO)
Corneal Sequestrum (Performed by Dr. Enry Garcia, DipACVO)

Publications

 一. Download (Articles in vets):

1. Veterinary Ophthalmology (2008) 11, 2, 61–66 Lamellar keratoplasty with a graft of lyophilized acellular porcine corneal stroma in the rabbit.pdf

2. Chinese Journal of Veterinary Medicine (2019)v.55(07) 78-80+126-127 A case report of using BioCorneaVet in treatment of cornea alkali burn on a dog (Chinese).pdf,2019,07:78-80+126-127)

3. Construction of tissue-engineered cornea composed of amniotic epithelial cells and acellular porcine cornea for treating corneal alkali burnHailangLuo, YongboLu,https://doi.org/10.1016/j.biomaterials.2013.05.045

4. Vet Times (https://vetspecialists.co.uk/case-studies-post/keratoplasty-using-a-new-corneal-xenograft-restores-pepes-vision/)

5. Cornea Ulcer grafts (https://vetspecialists.co.uk/fact-sheets-post/corneal-ulcer-grafts/)

6. Corneal graft from a pig saves dog’s sight (https://veterinaryrecord.bmj.com/content/185/14/423.3.full

7. Use of extracellular matrix (ECM) derived from porcine córnea (BioCorneaVET®) for the treatment of ocular perforation in dogs. {Uso de matriz extracelular (ECM) derivada de córnea suína (BioCorneaVET®) para o tratamento de perfuração ocular em cão. (P80-81)}(http://publicacoes.unifran.br/index.php/investigacao/issue/download/198/30)Uso de matriz extracelular (ECM) derivada de córnea suína (BioCorneaVET®) para o tratamento de perfuração ocular em cão. (P80-81)(http://publicacoes.unifran.br/index.php/investigacao/issue/download/198/30)

8. The Use of A Bio-Engineered Porcine Acellular Corneal Graft for the Treatment of Deep Corneal Defects in Dogs and Cats: 23 Eyes. JS Sapienza, D Micceri, EG da Silva and A Guandalini, 2019 ACVO abstract

二. Download (Articles in human)

1. American Journal of Transplantation 2015; 15: 1068–1075,doi: 10.1111/ajt.13096. Lamellar Keratoplasty Treatment of Fungal Corneal Ulcers With Acellular Porcine Corneal Stroma

2. Chin J Ophthalmol,2016,52: DOI: 10.3760/cma.j.issn.0412-4081.2016.03.0 Focus on the clinical application s of our country’s first artificial bioengineering cornea

3. Zheng J, Huang X, Zhang Y, et al. Short‐term results of acellular porcine corneal stroma keratoplasty for herpes simplex keratitis. Xenotransplantation.2019;e12509. https://doi.org/10.1111/xen.12509

4. Li S, Deng Y, Tian B, et al. Healing characteristics of acellular porcine corneal stroma following therapeutic keratoplasty. Xenotransplantation. 2019;00:e12566. https://doi.org/10.1111/xen.12566

 5. Shi Weiyun, Zhou Qingjun and etc. Protectively Decellularized Porcine Cornea versus Human Donor Cornea for Lamellar Transplantation. Advanced Functional Materials

6. Wang, Fuyan and Shi, Weiyun and etc, Decellularized Porcine Cornea-Based Hydrogels for Regeneration of Corneal Epithelium and Stroma. Available at SSRN: https://ssrn.com/abstract=3518167

7. L. Zhao, Y. Jia and C. Zhao et al. / Acta Biomaterialia 101 (2020) 344–356 

8. Dong M, Zhao L, Wang F, et al. Rapid porcine corneal decellularization through the use of sodium N-lauroyl glutamate and supernuclease. J Tissue Eng. 2019;10:2041731419875876. Published 2019 Sep 11. 

9. Li, Hua and Zhao, Long and Wang, Fuyan and Wang, Hongwei and Dong, Muchen and Liu, Ting and Ruan, Ting and Zhou, Mingming and Zhou, Qingjun and Xie, Lixin, Natural Cross-Linkers Stabilizedacellular Porcine Corneal Stroma for Lamellar Transplantation. Available at SSRN: https://ssrn.com/abstract=3560623 

Endorsements from Worldwide Veterinary Ophthalmologists

'At the moment I used 2 BioCorneaVet, they were both successful.The first case was a French Bulldog already treated with 2 previous biosis graft both failed for an infection from a Staphylococcus coagulase positive, 8 mm diameter. The second one was a Jack Russell Terrier with a corneal perforation , 5 mm diameter.' Oct 2018

'We used your product on 2 cases and they went very well. I do like it.' Feb 2018

'We have done at least 4 cases so far. All did well. Thanks again for your fine product.’Oct 2018

'I must say I am very impressed with your Biocornea Vet. I used them in 2 dogs so far. One was 10 mm large and the other 4 mm large. Both fine so far. They are 2 dogs a French bulldog and a terrier mix. I find it very easy to use, suture in place, etc. It seems to be well tolerated by the patient and have a very good integration with the donor cornea. We are for sure interested in offering this kind of corneal graft more often.' Oct 2018

Dr. Antonella Rampazzo  DVM, PhD, Dipl. ECVO Veterinary Ophthalmology Service Equine Department Vetsuisse Faculty, University of Zurich, Switzerland

" I believe BioCorneaVet is a great product for veterinary ophthalmologists who do not have a source of homologous fresh cornea available for transplantation; with a long shelf-life and no need for refrigeration, it is a great solution for immediate availability in cases of near full thickness stromal replacement, such as in descemetoceles and even small perforating corneal defects in dogs and cats." Mar 2020

Dr. Enry Garcia da Silva, DVM, MS, DACVO

'BioCorneaVet is a good choice for corneal transplantation because it is easy to provided. Ideal tissue incorporation and postoperative corneal transparency is well restored.' Nov 2018

Dr. Yi Dong, Executive President of CCVO

'BioCorneaVet is the most suitable graft for clinical use in small animals up to now. It has good histocompatibility and can obtain ideal optical effect after operation, even penetrating keratoplasty.' Dec 2018

Dr. Huihao Xu  Ph.D Southwest University of China

'It is fantastic! I work with cornea transplant since 2015 and I have some problems to collect and storing the cornea. With the BioCorneaVET we don`t have these kind of problems! And talking about the biologic effects, it looks like it is better or at list similar to the Frozen or preserved (Optsol).' Nov, 2018

Dr. Fabricio Mamede  Brazile